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Admin13.06.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Thresholds were set at 400 counts for AURKA and 540 counts for RPA1 Overall and progression-free survival dependent on gene expression of AURKA, RAD50 and DDB2.
1606
Admin24.06.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

4 Department of Pathology, Helios Klinikum Emil von Behring, Berlin, Germany.
2805
Admin28.07.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Therefore, 91 clinical MPM samples were digitally screened for gene expression patterns of HR members.
Admin18.06.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

The present data can lead to a better understanding of the underlaying cellular mechanisms and leave the door wide open for new therapeutic approaches for this severe disease with infaust prognosis.
6403
Admin27.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Survival of pleural malignant mesothelioma in Italy: a population-based study.
66010
Admin01.09.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

We hypothesize a major role of homologous recombination HR for genome stability and survival of this tumour.
703
Admin19.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Mairinger FD, Werner R, Flom E, Schmeller J, Borchert S, Wessolly M, et al.
7208
Admin05.08.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

Consent for publication Not applicable.
3206
Admin12.06.2021

Gene expression profiling of homologous recombination repair pathway indicates susceptibility for olaparib treatment in malignant pleural mesothelioma in vitro

2 Institute of Pathology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
5802